Anderlecht (1-0-1) are struggling both in Europe and domestically after losing to Borussia Dortmund in their last round and have fell to back to back draws in the Jupiter League.
The youth of the Belgian side could be their downfall as they face a depleted but experienced side in Arsenal.
Arsenal (2-0-0) still have a mountain of injury issues to deal with but nonetheless they should take all three points from their hosts.
Calum Chambers will be back for the Gunners but they continue to remain without several other key components to their best side, but should still have enough to secure a victory.
Projected Lineups
Anderlecht XI: Proto: Najar, Nuytinck, Mangulu, Deschacht; Defour, Tielemans; Conte, Praet, Acheampong; Mitrovic.
Arsenal XI: Martinez: Bellerin, Chambers, Mertesacker, Gibbs; Flamini; Sanchez, Wilshere, Cazorla, Oxlade-Chamberlain; Welbeck.